The original inhabitants of the area were Yuchi Indians. The first European settlers of Screven County were Germans who arrived in 1751. They were followed two years later by native-born American settlers who came mainly from the Carolinas and Virginia. In 1763, at the Southern Indian District Congress in Augusta, the Indians ceded the land between the Savannah River and the Ogeechee River.
Source: The New Georgia Encyclopedia - Screven County
Effingham, Jenkins and Burke Counties in addition to the South Carolina counties of Allendale and Hampton.